Papers: Online ahead of print

  1. Author Correction: Optogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation.
    Kawana Y, Imai J, Morizawa YM, Ikoma Y, Kohata M, Komamura H, Sato T, Izumi T, Yamamoto J, Endo A, Sugawara H, Kubo H, Hosaka S, Munakata Y, Asai Y, Kodama S, Takahashi K, Kaneko K, Sawada S, Yamada T, Ito A, Niizuma K, Tominaga T, Yamanaka A, Matsui K, Katagiri H.
    Nat Biomed Eng. Online ahead of print. doi: 10.1038/s41551-024-01200-y

  2. Translational response to mitochondrial stresses is orchestrated by tRNA modifications.
    Rashad S, Al-Mesitef S, Mousa A, Zhou Y, Ando D, Sun G, Fukuuchi T, Iwasaki Y, Xiang J, Byrne SR, Sun J, Maekawa M, Saigusa D, Begley TJ, Dedon PC, Niizuma K.
    bioRxiv. Online ahead of print. doi: 10.1101/2024.02.14.580389.

  3. Piezo Actuator-Driven Pulsed Water Jet for Neurosurgery: Laboratory Evaluation with the Swine Model and Implications of Mechanical Properties.
    Nakagawa A, Endo T, Kawaguchi T, Yamada M, Sato C, Kumabe T, Iwasaki M, Niizuma K, Kanamori M, Nakanishi C, Yamashita S, Nakano T, Tominaga T.
    J Neurol Surg A Cent Eur Neurosurg. Online ahead of print. doi: 10.1055/a-1962-1345.

Papers: 2024

  1. Optogenetic stimulation of vagal nerves for enhanced glucose-stimulated insulin secretion and β cell proliferation.
    Kawana Y, Imai J, Morizawa YM, Ikoma Y, Kohata M, Komamura H, Sato T, Izumi T, Yamamoto J, Endo A, Sugawara H, Kubo H, Hosaka S, Munakata Y, Asai Y, Kodama S, Takahashi K, Kaneko K, Sawada S, Yamada T, Ito A, Niizuma K, Tominaga T, Yamanaka A, Matsui K, Katagiri H.
    Nat Biomed Eng. 2024;8(7):808-822. doi: 10.1038/s41551-023-01113-2.

  2. Super-selective injection of propofol into the intracranial arteries enables Patient’s self-evaluation of expected neurological deficit.
    Osawa SI, Suzuki K, Ukishiro K, Kakinuma K, Ishida M, Niizuma K, Shimoda Y, Kikuchi H, Kochi R, Jin K, Matsumoto Y, Uematsu M, Nakasato N, Endo H, Tominaga T.
    Cortex. 2024;176:209-220. doi: 10.1016/j.cortex.2024.04.016 

  3. Distinguishing IDH mutation status in gliomas using FTIR-ATR spectra of peripheral blood plasma indicating clear traces of protein amyloid aggregation.
    Kino S, Kanamori M, Shimoda Y, Niizuma K, Endo H, Matsuura Y.
    BMC Cancer. 2024;24(1):222. doi: 10.1186/s12885-024-11970-y.

  4. Intravenously engrafted human multilineage-differentiating stress-enduring (Muse) cells rescue erectile function after rat cavernous nerve injury.
    Koyama J, Yamashita S, Kato Y, Nezu K, Goto T, Fujii S, Suzuki Y, Nakayashiki A, Kawasaki Y, Kawamorita N, Okita H, Ito T, Kushida Y, Goto M, Dezawa M, Tominaga T, Niizuma K, Ito A.
    BJU Int. 2024;133(3):332-340. doi: 10.1111/bju.16232.

  5. Assessment of language lateralization in epilepsy patients using the super-selective Wada test.
    Kakinuma K, Osawa SI, Katsuse K, Hosokawa H, Ukishiro K, Jin K, Niizuma K, Tominaga T, Endo H, Nakasato N, Suzuki K.
    Acta Neurochir (Wien)．2024;166(1):77. doi: 10.1007/s00701-024-05957-8.

  6. The prognostic values of plasma desmosines, crosslinking molecules of elastic fibers, in the disease progression of Moyamoya disease.
    Tashiro R, Anzawa R, Inoue T, Mikagi A, Ozaki D, Tominaga K, Inoue T, Ishida T, Fujimura M, Usuki T, Endo H, Niizuma K, Tominaga T.
    Bioorg Med Chem. 2024;100: 117602. doi: 10.1016/j.bmc.2024.117602.

  7. Cerebral venous sinus thrombosis detected using diffusion-weighted magnetic resonance imaging during maintenance temozolomide chemotherapy in a patient with glioblastoma: illustrative case.
    Takeuchi Y, Saito R, Kanamori M, Niizuma K, Mugikura S, Endo H.
    J Neurosurg Case Lessons. 2024;7(9): CASE23762. doi: 10.3171/CASE23762.

  8. [A Case of a Symptomatic Double-lumen Carotid Plaque Treated Using Carotid Endarterectomy Following Balloon Angioplasty].
    Mano Y, Haryu S, Yoshihara A, Saito N, Utsumi Y, Niizuma K, Sasaki T, Tominaga T.
    Surgery for Cerebral Stroke. 2024;52(1):23-29. doi: 10.2335/scs.52.23. Article in Japanese.

Papers: 2023

  1. Randomized placebo-controlled trial of CL2020, an allogenic muse cell-based product, in subacute ischemic stroke.
    Niizuma K, Osawa SI, Endo H, Izumi SI, Ataka K, Hirakawa A, Iwano M, Tominaga T.
    J Cereb Blood Flow Metab. 2023;43(12):2029-2039. doi: 10.1177/0271678X231202594.

  2. Intravenous Administration of Human Muse Cells Ameliorates Deficits in a Rat Model of Subacute Spinal Cord Injury.
    Takahashi Y, Kajitani T, Endo T, Nakayashiki A, Inoue T, Niizuma K, Tominaga T.
    Int J Mol Sci. 2023;24(19):14603. doi: 10.3390/ijms241914603.

  3. Six-month Outcomes after PulseRider- and Conventional Single Stent-assisted Embolization for Bifurcation Aneurysms: A Propensity-adjusted Comparison.
    Omodaka S, Matsumoto Y, Fujimori T, Sakata H, Sato K, Niizuma K, Endo H, Tominaga T.
    Neurol Med Chir (Tokyo). 2023; 63(11):512-518. doi: 10.2176/jns-nmc.2023-0082.

  4. Retiform endothelial hyperplasia mimicking cavernous malformation as a late complication of Gamma Knife radiosurgery.
    Kawagishi J, Jokura H, Watanabe M, Fujimura M, Niizuma K, Endo H, Suzuki H, Tominaga T.
    J Neurosurg. 2023; 139(1):165-175. doi: 10.3171/2022.

  5. A first-in-human study of the anti-inflammatory profibrinolytic TMS-007, an SMTP family triprenyl phenol.
    Moritoyo T, Nishimura N, Hasegawa K, Ishii S, Kirihara K, Takata M, Svensson AK, Umeda-Kameyama Y, Kawarasaki S, Ihara R, Sakanaka C, Wakabayashi Y, Niizuma K, Tominaga T, Yamazaki T, Hasumi K.
    Br J Clin Pharmacol. 2023; 89(6):1809-1819. doi: 10.1111/bcp.15651.

  6. Bilateral and asymmetrical localization of language function identified by the superselective infusion of propofol in an epilepsy patient with a mild malformation of cortical development: illustrative case.
    Otomo M, Osawa SI, Suzuki K, Kakinuma K, Ukishiro K, Suzuki H, Niizuma K, Narita N, Nakasato N, Tominaga T.
    J Neurosurg Case Lessons. 2023; 6(26):23451. doi: 10.3171/CASE23451.

  7. Olfactory Dysfunction, an Often Neglected Symptom of Hydrocephalus: Experience from a Case of Late-Onset Idiopathic Aqueductal Stenosis.
    Yamazaki N, Hasegawa T, Ikeda K, Miyata A, Osawa SI, Niizuma K, Kanno S, Tominaga T, Aoki M.
    Case Rep Neurol. 2023; 15(1): 41-47. doi: 10.1159/000529532.

Papers: 2022

  1. Isotope-dilution LC-MS/MS analysis of the elastin crosslinkers desmosine and isodesmosine in acute cerebral stroke patients.
    Mikagi A, Tashiro R, Inoue T, Anzawa R, Imura A, Tanigawa T, Ishida T, Inoue T, Niizuma K, Tominaga T, Usuki T.
    RSC Adv. 2022;12(49):31769-31777. doi: 10.1039/d2ra06009d.

  2. RNF213 loss of function reshapes vascular transcriptome and spliceosome leading to disrupted angiogenesis and aggravated vascular inflammatory responses.
    Zhang L, Rashad S, Zhou Y, Niizuma K, Tominaga T.
    J Cereb Blood Flow Metab. 2022;42(11):2107-2122. doi: 10.1177/0271678X221110679.

  3. Codon usage and mRNA stability are translational determinants of cellular response to canonical ferroptosis inducers.
    Rashad S, Byrne SR, Saigusa D, Xiang J, Zhou Y, Zhang L, Begley TJ, Tominaga T, Niizuma K.
    Neuroscience. 2022;201:103-130. doi: 10.1016/j.neuroscience.2022.08.009.

  4. Determination of language areas in patients with epilepsy using the super-selective Wada test.
    Kakinuma K, Osawa SI, Hosokawa H, Oyafuso M, Ota S, Kobayashi E, Kawakami N, Ukishiro K, Jin K, Ishida M, Sato T, Sakamoto M, Niizuma K, Tominaga T, Nakasato N, Suzuki K.
    IBRO Neurosci Rep. 2022;13:156-163. doi: 10.1016/j.ibneur.2022.08.002.

  5. Effects of clazosentan on cerebral vasospasm-related morbidity and all-cause mortality after aneurysmal subarachnoid hemorrhage: two randomized phase 3 trials in Japanese patients.
    Endo H, Hagihara Y, Kimura N, Takizawa K, Niizuma K, Togo O, Tominaga T.
    J Neurosurg. 2022;137(6):1707-1717. doi: 10.3171/2022.2.JNS212914.

  6. Plasma tRNA derivatives concentrations for detecting early brain damage in patients with acute large vessel occlusion and predicting clinical outcomes after endovascular thrombectomy.
    Ishida T, Inoue T, Niizuma K, Inoue T, Sasaki K, Sakata H, Ezura M, Uenohara H, Abe T, Tominaga T.
    Clin Neurol Neurosurg. 2022;220:107358. doi: 10.1016/j.clineuro.2022.107358.

  7. Wall enhancement in unruptured posterior communicating aneurysms with oculomotor nerve palsy on magnetic resonance vessel wall imaging.
    Omodaka S, Endo H, Niizuma K, Endo T, Sato K, Saito A, Uchida H, Matsumoto Y, Tominaga T.
    J Neurosurg. 2022;137(3):668–674. doi: 10.3171/2021.11.JNS212249.

  8. Development and validation of machine learning prediction model for post-rehabilitation functional outcome after intracerebral hemorrhage.
    Sonobe S, Ishikawa T, Niizuma K, Kawakami E, Ueda T, Takaya E, Makoto Miyauchi C, Iwazaki J, Kochi R, Endo T, Shastry A, Jagannatha V, Seth A, Nakagawa A, Yoshida M, Tominaga T.
    Interdiscip Neurosurg: Adv Tech Case Manag. 2022;29:101560. doi: 10.1016/j.inat.2022.101560.

  9. Quantitative assessment of microstructural evolution of intracranial aneurysm wall by vessel wall imaging.
    Endo H, Mori N, Mugikura S, Niizuma K, Omodaka S, Takase K, Tominaga T.
    Neuroradiology. 2022;64(7):1343-1350. doi: 10.1007/s00234-021-02877-7.

  10. Morphological comparison of masseter muscle fibres in the mandibular rest and open positions using diffusion tensor imaging.
    Sugano T, Ogawa T, Yoda N, Hashimoto T, Shobara K, Niizuma K, Kawashima R, Sasaki K.
    J Oral Rehabil. 2022;49(6):608-615. doi: 10.1111/joor.13319.

  11. Intraoperative motor-evoked potential monitoring during coil embolization for anterior choroidal artery aneurysms.
    Ito A, Sato K, Niizuma K, Endo H, Matsumoto Y, Tominaga T.
    Neuroradiology. 2022;64(6):1221-1229. doi: 10.1007/s00234-021-02847-z.

  12. Association between RNF213 c.14576G>A Variant (rs112735431) and Peripheral Pulmonary Artery Stenosis in Moyamoya Disease.
    Ozaki D, Endo H, Tahiro R, Sugimura K, Tatebe S, Yasuda S, Tomota Y, Endo T, Tominaga K, Niizuma K, Fujimura M, Tominaga T.
    Cerebrovasc Dis. 2022;51(3):282-287. doi: 10.1159/000519717.

  13. Prediction of atherosclerotic changes in cavernous carotid aneurysms based on computational fluid dynamics analysis: a proof-of-concept study.
    Nakajima S, Sugiyama S, Oishi H, Sato K, Matsumoto Y, Niizuma K, Fujimura M, Tominaga T.
    Neuroradiology. 2022;64(3):575-585. doi: 10.1007/s00234-021-02803-x.

  14. Efficacy of ultra-high-resolution computed tomographic angiography for postoperative evaluation of intracranial aneurysm after clipping surgery: A case report.
    Kayano S, Ito A, Endo T, Nemoto H, Shimada K, Niizuma K, Tominaga T.
    Surg Neurol Int. 2022;13:85. doi: 10.25259/SNI_1190_2021. eCollection 2022.

  15. Methodological assessment of the reduction of dissemination risk and quantification of debris dispersion during dissection with a surgical aspirator.
    Kageyama S, Nakagawa A, Kawaguchi T, Ohtani K, Endo T, Kyan M, Kusunoki T, Shimoda Y, Osawa SI, Kanamori M, Niizuma K, Tominaga T.
    BMC Res Notes. 2022;15(1):85. doi: 10.1186/s13104-022-05947-y.

  16. Application of Diffusion Tensor Imaging Fiber Tractography for Human Masseter Muscle.
    Sugano T, Yoda N, Ogawa T, Hashimoto T, Shobara K, Niizuma K, Kawashima R, Sasaki K.
    Tohoku J Exp Med. 2022;256(2):151-160. doi: 10.1620/tjem.256.151.

  17. Non-Kolmogorov turbulence in carotid artery stenosis and the impact of carotid stenting on near-wall turbulence.
    Saqr KM, Kano K, Rashad S, Niizuma K, Kaku Y, Iwama T, Tominaga T.
    AIP Advances. 2022;12(1):0076271. doi: 10.1063/5.0076271.

Papers: 2021

  1. Comparison between ultra-high-resolution computed tomographic angiography and conventional computed tomographic angiography in the visualization of the subcallosal artery.
    Sato Y, Endo T, Kayano S, Nemoto H, Shimada K, Ito A, Endo H, Mugikura S, Niizuma K, Tominaga T.
    Surg Neurol Int. 2021;12:528. doi: 10.25259/SNI_887_2021.

  2. Carotid computed tomography angiography after cobalt-based alloy carotid artery stenting using ultra-high-resolution computed tomography with model-based iterative reconstruction.
    Kayano S, Ota H, Sato Y, Endo T, Niizuma K, Suzuki I, Kawamura T, Takase K.
    Radiol Case Rep. 2021;16(12):3721-3728. doi: 10.1016/j.radcr.2021.09.003.

  3. Computational hemodynamic analysis of the offending vertebral artery at the site of neurovascular contact in a case of hemifacial spasm associated with subclavian steal syndrome: illustrative case.
    Tominaga K, Endo H, Sugiyama SI, Osawa SI, Niizuma K, Tominaga T.
    J Neurosurg Case Lessons. 2021;2(12):CASE21447. doi: 10.3171/CASE21447.

  4. A Super-selective Wada Test Successfully Detected an Artery That Supplied Broca’s Area in a Case of Left Frontal Lobe Glioblastoma: Technical Case Report.
    Yamashita S, Saito R, Osawa SI, Niizuma K, Ukishiro K, Kanamori M, Kakinuma K, Suzuki K, Tominaga T.
    Neurol Med Chir (Tokyo). 2021;61(11):661-666. doi: 10.2176/nmc.tn.2021-0054.

  5. Dysregulation of Rnf 213 gene contributes to T cell response via antigen uptake, processing, and presentation.
    Tashiro R, Niizuma K, Kasamatsu J, Okuyama Y, Rashad S, Kikuchi A, Fujimura M, Kure S, Ishii N, Tominaga T.
    J Cell Physiol. 2021;236(11):7554-7564. doi: 10.1002/jcp.30396.

  6. Effect of endoscope flexibility on tissue dissection profile assessed with pulsed water jet device: ensuring safety, efficacy, and handling of thin devices for neuroendoscopic surgery.
    Kusunoki T, Kawaguchi T, Nakagawa A, Noguchi Y, Osawa SI, Endo H, Endo T, Saito R, Kanamori M, Niizuma K, Tominaga T.
    BMC Res Notes. 2021;14(1):64. doi: 10.1186/s13104-021-05475-1.

  7. Prolonged/delayed cerebral hyperperfusion in adult patients with moyamoya disease with RNF213 gene polymorphism c.14576G>A (rs112735431) after superficial temporal artery-middle cerebral artery anastomosis.
    Tashiro R, Fujimura M, Katsuki M, Nishizawa T, Tomata Y, Niizuma K, Tominaga T.
    J Neurosurg. 2021;135(2):417-424. doi: 10.3171/2020.6.JNS201037.

  8. Digital intravascular pressure wave recording during endovascular treatment reveals abnormal shunting flow in vertebral venous fistula of the vertebral artery: illustrative case.
    Shimoda Y, Sonobe S, Niizuma K, Endo T, Endo H, Otomo M, Tominaga T.
    J Neurosurg Case Lessons. 2021;2(2):CASE21172. doi: 10.3171/CASE21172.

  9. Ocular neuromyotonia caused by a recurrent sphenoidal ridge meningioma.
    Shingai Y, Endo H, Endo T, Osawa SI, Niizuma K, Tominaga T.
    Surg Neurol Int. 2021;12:219. doi: 10.25259/SNI_38_2021.

  10. Basilar artery dissection with rupture 6 years after accidental detection: A case report.
    Sato Y, Niizuma K, Ota H, Endo H, Tominaga T.
    Surg Neurol Int. 2021;12:4. doi: 10.25259/SNI_735_2020.

  11. Brain Temperature Measured by Magnetic Resonance Spectroscopy to Predict Clinical Outcome in Patients with Infarction.
    Ishida T, Inoue T, Inoue T, Endo T, Fujimura M, Niizuma K, Endo H, Tominaga T.
    Sensors (Basel). 2021;21(2):490. doi: 10.3390/s21020490.

  12. Association of intravenous administration of human Muse cells with deficit amelioration in a rat model of spinal cord injury.
    Kajitani T, Endo T, Iwabuchi N, Inoue T, Takahashi Y, Abe T, Niizuma K, Tominaga T.
    J Neurosurg Spine. 2021;34(4):648-655. doi: 10.3171/2020.7.SPINE20293.

  13. The cell and stress-specific canonical and noncanonical tRNA cleavage.
    Rashad S, Tominaga T, Niizuma K.
    J Cell Physiol. 2021 May;236(5):3710-3724. doi: 10.1002/jcp.30107.

  14. [A Case of Cavernous Sinus Dural Arteriovenous Fistula Successfully Treated by Transarterial Embolization with Embosphere].
    Chen M, Osawa SI, Niizuma K, Endo H, Tominaga T.
    No Kekkannai Chiryo. 2021;6(1):38-43. doi: 10.20626/nkc.cr.2020-0021. Article in Japanese.

  15. Prediction of Functional Outcome in Patients with Acute Stroke by Measuring tRNA Derivatives.
    Ishida T, Inoue T, Niizuma K, Konno N, Suzuki C, Inoue T, Ezura M, Uenohara H, Abe T, Tominaga T.
    Cerebrovasc Dis. 2020;49(6):639-646. doi: 10.1159/000511627.

  16. XGBoost, a Machine Learning Method, Predicts Neurological Recovery in Patients with Cervical Spinal Cord Injury.
    Inoue T, Ichikawa D, Ueno T, Cheong M, Inoue T, Whetstone WD, Endo T, Niizuma K, Tominaga T.
    Neurotrauma Rep. 2020;1(1):8-16. doi: 10.1089/neur.2020.0009.

  17. Preliminary study of eye tracking to investigate the differences in gaze behaviors depending on the experience of neuroendovascular therapy.
    Shojima M, Okamoto Y, Niizuma K, Ohta M, Ishikawa O, Fujisawa A, Tsukihara H, Sakai N, Tominaga T.
    Surg Neurol Int. 2020;11:351. doi: 10.25259/SNI_543_2020.

  18. Physiologic blood flow is turbulent.
    Saqr KM, Tupin S, Rashad S, Endo T, Niizuma K, Tominaga T, Ohta M.
    Sci Rep. 2020;10(1):15492. doi: 10.1038/s41598-020-72309-8.

  19. Direct Inspection with Dual Endoscope Technique via Bilateral Transforaminal Approach Leading to Complete Resection of Recurrent Colloid Cyst of the Third Ventricle.
    Nakayashiki A, Kawaguchi T, Niizuma K, Watanabe M, Fujimura M, Tominaga T.
    World Neurosurg. 2020;141:272-277. doi: 10.1016/j.wneu.2020.06.060.

  20. Intractable Hiccups as the Primary Symptom of a Perimedullary Arteriovenous Fistula at the Craniocervical Junction.
    Sasaki K, Inoue T, Inoue T, Nishijima Y, Endo T, Ezura M, Uenohara H, Niizuma K, Tominaga T.
    World Neurosurg. 2020;141:64-68. doi: 10.1016/j.wneu.2020.06.013.

  21. A Novel Type of Stem Cells Double-Positive for SSEA-3 and CD45 in Human Peripheral Blood.
    Sato T, Wakao S, Kushida Y, Tatsumi K, Kitada M, Abe T, Niizuma K, Tominaga T, Kushimoto S, Dezawa M.
    Cell Transplant. 2020;29:963689720923574. doi: 10.1177/0963689720923574.

  22. The stress specific impact of ALKBH1 on tRNA cleavage and tiRNA generation.
    Rashad S, Han X, Sato K, Mishima E, Abe T, Tominaga T, Niizuma K.
    RNA Biol. 2020;17(8):1092-1103. doi: 10.1080/15476286.2020.1779492.

  23. Preliminary Study of Eye-Tracking During the Coil Insertion Task in a Silastic Model of Intracranial Aneurysms.
    Shojima M, Okamoto Y, Ohta M, Niizuma K, Sakai N, Tominaga T.
    World Neurosurg. 2020;139:e827-e835. doi: 10.1016/j.wneu.2020.05.012.

  24. Ruptured Basilar Artery Dissection Diagnosed Using Magnetic Resonance Vessel Wall Imaging and Treated with Coil Embolization with Overlapping LVIS Stents: A Case Report.
    Sonobe S, Yoshida M, Niizuma K, Tominaga T.
    NMC Case Rep J. 2020;7(2):75-79. doi: 10.2176/nmccrj.cr.2019-0141.

  25. Metabolic basis of neuronal vulnerability to ischemia; an in vivo untargeted metabolomics approach.
    Rashad S, Saigusa D, Yamazaki T, Matsumoto Y, Tomioka Y, Saito R, Uruno A, Niizuma K, Yamamoto M, Tominaga T.
    Sci Rep. 2020;10(1):6507. doi: 10.1038/s41598-020-63483-w.

  26. Efficacy of intra-arterial indocyanine green angiography for the microsurgical treatment of dural arteriovenous fistula: A case report.
    Sasaki K, Endo H, Niizuma K, Nishijima Y, Osawa S, Fujimura M, Tominaga T.
    Surg Neurol Int. 2020;11:46. doi: 10.25259/SNI_588_2019.

  27. Stress Induced tRNA Halves (tiRNAs) as Biomarkers for Stroke and Stroke Therapy; Pre-clinical Study.
    Sato K, Rashad S, Niizuma K, Tominaga T. 
    Neuroscience. 2020;434:44-54. doi: 10.1016/j.neuroscience.2020.03.018.

  28. Case reports of latent HBV hepatitis in patients after neurosurgical treatment for hypothalamic and pituitary tumors.
    Niizuma K, Ogawa Y, Kogure T, Tominaga T.
    BMC Infect Dis. 2020;20(1):230. doi: 10.1186/s12879-020-04971-2.

  29. The hemodynamic complexities underlying transient ischemic attacks in early-stage Moyamoya disease: an exploratory CFD study.
    Rashad S, Saqr KM, Fujimura M, Niizuma K, Tominaga T.
    Sci Rep. 2020;10(1):6217. doi: 10.1038/s41598-020-62862-7.

  30. Symptomatic cerebral hyperperfusion following cerebral vasospasm associated with aneurysmal subarachnoid hemorrhage: a case report.
    Sakata H, Endo H, Fujimura M, Niizuma K, Tominaga T.
    World Neurosurg. 2020;137:379-383. doi: 10.1016/j.wneu.2020.02.092.

  31. Octacalcium phosphate collagen composite (OCP/Col) enhance bone regeneration in a rat model of skull defect with dural defect.
    Sasaki T, Niizuma K, Kanoke A, Matsui K, Ogita S, Rashad S, Kawai T, Watanabe M, Endo H, Takahashi T, Kamakura S, Tominaga T.
    Heliyon. 2020;6(2):e03347. doi: 10.1016/j.heliyon.2020.e03347.

  32. Optimal Timing of Extracranial-Intracranial Bypass with Microsurgical Trapping for Ruptured Blister Aneurysms of the Internal Carotid Artery.
    Endo H, Fujimura M, Shimizu H, Endo T, Omodaka S, Inoue T, Sato K, Niizuma K, Tominaga T.
    World Neurosurg. 2020;136:e567-e577. doi: 10.1016/j.wneu.2020.01.081.

  33. A novel model of cerebral hyperperfusion with blood-brain barrier breakdown, white matter injury, and cognitive dysfunction.
    Mansour A, Rashad S, Niizuma K, Fujimura M, Tominaga T.
    J Neurosurg. 2020;135(5):1460-1472. doi: 10.3171/2019.7.JNS19212.

  34. Epigenetic response of endothelial cells to different wall shear stress magnitudes: A report of new mechano-miRNAs.
    Rashad S, Han X, Saqr K, Tupin S, Ohta M, Niizuma K, Tominaga T.
    J Cell Physiol. 2020;235(11):7827-7839. doi: 10.1002/jcp.29436.

  35. Intravenously Transplanted Human Multilineage-Differentiating Stress-Enduring Cells Afford Brain Repair in a Mouse Lacunar Stroke Model.
    Abe T, Aburakawa D, Niizuma K, Iwabuchi N, Kajitani T, Wakao S, Kushida Y, Dezawa M, Borlongan CV, Tominaga T.
    Stroke. 2020;51(2):601-611. doi: 10.1161/STROKEAHA.119.026589.

  36. Unilateral chronic subdural hematoma due to spontaneous intracranial hypotension: a report of four cases.
    Osada Y, Shibahara I, Nakagawa A, Sakata H, Niizuma K, Saito R, Kanamori M, Fujimura M, Suzuki S, Tominaga T.
    Br J Neurosurg. 2020;34(6):632-637. doi: 10.1080/02688697.2019.1667482.

  37. Regression of Recurrent Spinal Cord High-Grade Glioma After Convection-Enhanced Delivery of Nimustine Hydrochloride: Case Reports and Literature Review.
    Endo T, Inoue T, Sugiyama S, Saito R, Tominaga T.
    Oper Neurosurg (Hagerstown). 2020;18(4):451-459. doi: 10.1093/ons/opz172.

  38. Significance of Quantitative Cerebral Blood Flow Measurement in the Acute Stage after Revascularization Surgery for Adult Moyamoya Disease: Implication for the Pathological Threshold of Local Cerebral Hyperperfusion.
    Kameyama M, Fujimura M, Tashiro R, Sato K, Endo H, Niizuma K, Mugikura S, Tominaga T.
    Cerebrovasc Dis. 2020;48(3-6):217-225. doi: 10.1159/000504835.

Papers: 2019

  1. Experience of Low Dose Perampanel to Add-on in Glioma Patients with Levetiracetam-uncontrollable Epilepsy.
    Chonan M, Saito R, Kanamori M, Osawa SI, Watanabe M, Suzuki H, Nakasato N, Tominaga T.
    Neurol Med Chir (Tokyo). 2020;60(1):37-44. doi: 10.2176/nmc.oa.2018-0245.

  2. Cystic Glioblastoma Rupturing into the Ventricle.
    Sato Y, Saito R, Kanamori M, Tominaga T.
    NMC Case Rep J. 2019;7(1):39-41. doi: 10.2176/nmccrj.cr.2019-0043.

  3. Arterial blood pressure correlates with 90-day mortality in sepsis patients: a retrospective multicenter derivation and validation study using high-frequency continuous data.
    Kobayashi N, Nakagawa A, Kudo D, Ishigaki T, Ishizuka H, Saito K, Ejima Y, Wagatsuma T, Toyama H, Kawaguchi T, Niizuma K, Ando K, Kurotaki K, Kumagai M, Kushimoto S, Tominaga T, Yamauchi M.
    Blood Press Monit. 2019;24(5):225-233. doi: 10.1097/MBP.0000000000000398.

  4. Identification of HLA-DRB1*04:10 allele as risk allele for Japanese moyamoya disease and its association with autoimmune thyroid disease: A case-control study.
    Tashiro R, Niizuma K, Khor SS, Tokunaga K, Fujimura M, Sakata H, Endo H, Inoko H, Ogasawara K, Tominaga T.
    PLoS One. 2019;14(8):e0220858. doi: 10.1371/journal.pone.0220858.

  5. Incidence and Risk Factors of the Watershed Shift Phenomenon after Superficial Temporal Artery-Middle Cerebral Artery Anastomosis for Adult Moyamoya Disease.
    Tashiro R, Fujimura M, Kameyama M, Mugikura S, Endo H, Takeuchi Y, Tomata Y, Niizuma K, Tominaga T.
    Cerebrovasc Dis. 2019;47(3-4):178-187. doi: 10.1159/000500802.

  6. Genetic analysis of ring finger protein 213 (RNF213) c.14576G>A polymorphism in patients with vertebral artery dissection: a comparative study with moyamoya disease.
    Tashiro R, Fujimura M, Sakata H, Endo H, Tomata Y, Sato-Maeda M, Niizuma K, Tominaga T.
    Neurol Res. 2019;41(9):811-816. doi: 10.1080/01616412.2019.1615726.

  7. Neuroprotective effects of minocycline and progesterone on white matter injury after focal cerebral ischemia.
    Faheem H, Mansour A, Elkordy A, Rashad S, Shebl M, Madi M, Elwy S, Niizuma K, Tominaga T.
    J Clin Neurosci. 2019;64:206-213. doi: 10.1016/j.jocn.2019.04.012.

  8. tiRNAs as a novel biomarker for cell damage assessment in in vitro ischemia-reperfusion model in rat neuronal PC12 cells.
    Elkordy A, Rashad S, Shehabeldeen H, Mishima E, Niizuma K, Abe T, Tominaga T.
    Brain Res. 2019;1714:8-17. doi: 10.1016/j.brainres.2019.02.019.

  9. Transsphenoidal Removal of Retroclival Chondroma with Pituitary Transposition Manifesting as Repeated Subarachnoid Hemorrhage: A Case Report.
    Ogawa Y, Niizuma K, Tominaga T.
    J Neurol Surg A Cent Eur Neurosurg. 2019;80(3):228-232. doi: 10.1055/s-0038-1677452.

  10. Cord Compression Caused by a Tangled and Warped Lumbar Catheter After Lumboperitoneal Shunt Placement.
    Sato K, Endo T, Sakata H, Inoue T, Niizuma K, Tominaga T.
    Neurospine. 2019;16(2):368-372. doi: 10.14245/ns.1836114.057.

  11. Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage.
    Inoue T, Ishida T, Inoue T, Saito A, Ezura M, Uenohara H, Fujimura M, Sato K, Endo T, Omodaka S, Endo H, Niizuma K, Tominaga T.
    J Stroke Cerebrovasc Dis. 2019;28(2):490-494. doi: 10.1016/j.jstrokecerebrovasdis.2018.10.027.

  12. Coexistence of Intracranial Germ Cell Tumor with Growing Arteriovenous Fistula.
    Ishida T, Endo H, Saito R, Kanamori M, Sato K, Matsumoto Y, Endo T, Fujimura M, Tominaga T.
    World Neurosurg. 2019;127:126-130. doi: 10.1016/j.wneu.2019.04.015. 

  13. Circumferential wall enhancement in evolving intracranial aneurysms on magnetic resonance vessel wall imaging.
    Omodaka S, Endo H, Niizuma K, Fujimura M, Inoue T, Endo T, Sato K, Sugiyama SI, Tominaga T.
    J Neurosurg. 2019;131(4):1262–1268. doi: 10.3171/2018.5.JNS18322. 

  14. Mechanical Thrombectomy for Acute Ischemic Stroke Arising from Thrombus of the Left Superior Pulmonary Vein Stump after Left Pneumonectomy: A Case Report.
    Sonobe S, Yoshida M, Niizuma K, Tominaga T.
    NMC Case Rep J. 2019;6(1):17-20. doi: 10.2176/nmccrj.cr.2018-0163.

  15. A refined model of chronic cerebral hypoperfusion resulting in cognitive impairment and a low mortality rate in rats.
    Mansour A, Niizuma K, Rashad S, Sumiyoshi A, Ryoke R, Endo H, Endo T, Sato K, Kawashima R, Tominaga T.
    J Neurosurg. 2019;131(3):892-902. doi: 10.3171/2018.3.JNS172274.

  16. Incidence of initial spinal metastasis in glioblastoma patients and the importance of spinal screening using MRI.
    Shibahara I, Saito R, Osada Y, Kanamori M, Sonoda Y, Kumabe T, Mugikura S, Watanabe M, Tominaga T.
    J Neurooncol. 2019;141(2):337-345. doi: 10.1007/s11060-018-03036-4.

Papers: 2018

  1. Real-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress: The 2015 International Aneurysm CFD Challenge.
    Valen-Sendstad K, Bergersen AW, Shimogonya Y, Goubergrits L, Bruening J, Pallares J, Cito S, Piskin S, Pekkan K, Geers AJ, Larrabide I, Rapaka S, Mihalef V, Fu W, Qiao A, Jain K, Roller S, Mardal KA, Kamakoti R, Spirka T, Ashton N, Revell A, Aristokleous N, Houston JG, Tsuji M, Ishida F, Menon PG, Browne LD, Broderick S, Shojima M, Koizumi S, Barbour M, Aliseda A, Morales HG, Lefèvre T, Hodis S, Al-Smadi YM, Tran JS, Marsden AL, Vaippummadhom S, Einstein GA, Brown AG, Debus K, Niizuma K, Rashad S, Sugiyama SI, Owais Khan M, Updegrove AR, Shadden SC, Cornelissen BMW, Majoie CBLM, Berg P, Saalfield S, Kono K, Steinman DA.
    Cardiovasc Eng Technol. 2018;9(4):544-564. doi: 10.1007/s13239-018-00374-2.

  2. Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation.
    Berg P, Voß S, Saalfeld S, Janiga G, Bergersen AW, Valen-Sendstad K, Bruening J, Goubergrits L, Spuler A, Cancelliere NM, Steinman DA, Pereira VM, Chiu TL, Tsang ACO, Chung BJ, Cebral JR, Cito S, Pallarès J, Copelli G, Csippa B, Paál G, Fujimura S, Takao H, Hodis S, Hille G, Karmonik C, Elias S, Kellermann K, Khan MO, Marsden AL, Morales HG, Piskin S, Finol EA, Pravdivtseva M, Rajabzadeh-Oghaz H, Paliwal N, Meng H, Seshadhri S, Howard M, Shojima M, Sugiyama SI, Niizuma K, Sindeev S, Frolov S, Wagner T, Brawanski A, Qian Y, Wu YA, Carlson KD, Dragomir-Daescu D, Beuing O.
    Cardiovasc Eng Techn. 2018;9(4):565-581. doi: 10.1007/s13239-018-00376-0.

  3. Quantitative Characterization of Carotid Plaque Components Using MR Apparent Diffusion Coefficients and Longitudinal Relaxation Rates at 3T: A Comparison With Histology.
    Ota H, Tamura H, Itabashi R, Yazawa Y, Nakamura Y, Hisamatsu K, Takamatsu M, Endo H, Niizuma K, Enomoto Y, Nagasaka T, Kajita K, Watanabe M, Yoshimura S, Yuan C.
    J Magn Reson Imaging. 2018;48(6):1657-1667. doi: 10.1002/jmri.26216.

    Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumors.
    Fukuoka K, Saito R et al.; Japan Pediatric Molecular Neuro-Oncology Group (JPMNG).
    Acta Neuropathol Commun. 2018;6(1):134. doi: 10.1186/s40478-018-0630-1.

  4. Early BBB breakdown and subacute inflammasome activation and pyroptosis as a result of cerebral venous thrombosis.
    Rashad S, Niizuma K, Sato-Maeda M, Fujimura M, Mansour A, Endo H, Ikawa S, Tominaga T.
    Brain Res. 2018;1699:54-68. doi: 10.1016/j.brainres.2018.06.029.

  5. Biphasic Development of Focal Cerebral Hyperperfusion After Revascularization Surgery for Adult Moyamoya Disease Associated With Autosomal Dominant Polycystic Kidney Disease.
    Tashiro R, Fujimura M, Endo H, Endo T, Niizuma K, Tominaga T.
    J Stroke Cerebrovasc Dis. 2018;27(11):3256-3260. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.024.

  6. Metabolomic Analysis of Mouse Brain after a Transient Middle Cerebral Artery Occlusion by Mass Spectrometry Imaging.
    Abe T, Niizuma K, Kanoke A, Saigusa D, Saito R, Uruno A, Fujimura M, Yamamoto M, Tominaga T.
    Neurol Med Chir (Tokyo). 2018;58(9):384-392. doi: 10.2176/nmc.oa.2018-0054.

  7. Stress-induced tRNA cleavage and tiRNA generation in rat neuronal PC12 cells.
    Elkordy A, Mishima E, Niizuma K, Akiyama Y, Fujimura M, Tominaga T, Abe T.
    J Neurochem. 2018;146(5):560-569. doi: 10.1111/jnc.14321.

  8. Paradoxical Association of Symptomatic Local Vasogenic Edema with Global Cerebral Hypoperfusion after Direct Revascularization Surgery for Adult Moyamoya Disease.
    Tashiro R, Fujimura M, Mugikura S, Niizuma K, Endo H, Endo T, Tominaga T.
    J Stroke Cerebrovasc Dis. 2018;27(8):e172-e176. doi: 10.1016/j.jstrokecerebrovasdis.2018.03.002.

  9. Intracellular S1P Levels Dictate Fate of Different Regions of the Hippocampus following Transient Global Cerebral Ischemia.
    Rashad S, Niizuma K, Saigusa D, Han X, Sato-Maeda M, Saito R, Uruno A, Fujimura M, Ikawa S, Yamamoto M, Tominaga T.
    Neuroscience. 2018;384:188-202. doi: 10.1016/j.neuroscience.2018.05.015.

  10. [Surgical Planning for a Giant Pituitary Adenoma Based on Evaluation of the Fine Feeding System and Angioarchitecture:A Case Report].
    Aburakawa D, Ogawa Y, Sato K, Niizuma K, Tominaga T. 
    No Shinkei Geka. 2018;46(8):691-697. doi: 10.11477/mf.1436203795. Article in Japanese.

  11. Mid-term prognosis of non-functioning pituitary adenomas with high proliferative potential: really an aggressive variant?
    Ogawa Y, Jokura H, Niizuma K, Tominaga T.
    J Neurooncol. 2018;137(3):543-549. doi: 10.1007/s11060-017-2740-1.

  12. Circumferential Wall Enhancement on Magnetic Resonance Imaging is Useful to Identify Rupture Site in Patients with Multiple Cerebral Aneurysms.
    Omodaka S, Endo H, Niizuma K, Fujimura M, Endo T, Sato K, Sugiyama SI, Inoue T, Tominaga T.
    Neurosurgery. 2018;82(5):638-644. doi: 10.1093/neuros/nyx267.

  13. Impact of bifurcation angle and inflow coefficient on the rupture risk of bifurcation type basilar artery tip aneurysms.
    Rashad S, Sugiyama SI, Niizuma K, Sato K, Endo H, Omodaka S, Matsumoto Y, Fujimura M, Tominaga T.
    J Neurosurg. 2018;128(3):723-730. doi: 10.3171/2016.10.JNS161695.

  14. Clinical Characteristics of Lumbosacral Spinal Dural Arteriovenous Fistula (DAVF)-Comparison with Thoracic DAVF.
    Endo T, Kajitani T, Inoue T, Sato K, Niizuma K, Endo H, Matsumoto Y, Tominaga T.
    World Neurosurg. 2018;110:e383-e388. doi: 10.1016/j.wneu.2017.11.002.

  15. Increased serum production of soluble CD163 and CXCL5 in patients with moyamoya disease: Involvement of intrinsic immune reaction in its pathogenesis.
    Fujimura M, Fujimura T, Kakizaki A, Sato-Maeda M, Niizuma K, Tomata Y, Aiba S, Tominaga T.
    Brain Res. 2018;1679:39-44. doi: 10.1016/j.brainres.2017.11.013.

  16. Embolization of ruptured arteriovenous malformations in the cerebellopontine angle cistern.
    Endo H, Osawa SI, Matsumoto Y, Endo T, Sato K, Niizuma K, Fujimura M, Tominaga T.
    Neurosurg Rev. 2018;41(1):173-182. doi: 10.1007/s10143-017-0832-1.

  17. Patient with Recurrent Anterior Cerebral Artery Dissecting Aneurysm After Stent-Assisted Coil Embolization Successfully Treated with A3-A3 Anastomosis.
    Takahashi Y, Endo H, Endo T, Fujimura M, Niizuma K, Tominaga T.
    World Neurosurg. 2018;109:77-81. doi: 10.1016/j.wneu.2017.09.128.

Review articles: Online ahead of print

Review articles

  1. Donor Muse Cell Treatment Without HLA-Matching Tests and Immunosuppressant Treatment.
    Minatoguchi S, Fujita Y, Niizuma K, Tominaga T, Yamashita T, Abe K, Dezawa M.
    Stem Cells Transl Med. 2024;13(6):532-545. doi: 10.1093/stcltm/szae018.

  2. Endovascular Treatment of Wide-Neck Bifurcation Aneurysm: Recent Trends in Coil Embolization with Adjunctive Technique.
    Haryu S, Sakata H, Matsumoto Y, Niizuma K, Endo H.
    J Neuroendovasc. 2024;18(3):75-83. doi: 10.5797/jnet.ra.2023-0072.

  3. [Academia-Industry Alliance: Recent Trend].
    Nakagawa A, Perl L, Lee J, Harada-Shoji N, Ota C, Shiga T, Sunami S, Niizuma K, Endo H, Harigae H, Tominaga T.
    No Shinkei Geka. 2024;52(1):213-225. doi: 10.11477/mf.1436204899. Article in Japanese.

  4. [Stem Cell Therapy for Neurological Diseases].
    Niizuma K.
    Brain Nerve. 2023;75(2): 167-172. doi: 10.11477/mf.1416202299. Article in Japanese.

  5. [Muse cell transplantation therapy for the spinal cord injury].
    Endo T, Niizuma K, Tominaga T.
    J Joint Surgery. 2022;41(3):231-236. doi: 10.18885/JJS.0000000913. Article in Japanese.

  6. [Development of muse cell therapy for ischemic stroke].
    Niizuma K.
    Jpn J Thrombosis and Hemostasis. 2021;32(3):296-302. doi: 10.2491/jjsth.32.296. Article in Japanese.

  7. [Development of Muse cell therapy for ischemic stroke].
    Niizuma K, Tominaga T.
    Jpn J Neuropsychology. 2021;37(1):21-28. doi: 10.20584/neuropsychology.17106. Article in Japanese.

  8. tRNA cleavage: a new insight.
    Rashad S, Niizuma K, Tominaga T.
    Neural Regen Res. 2020;15(1):47-52. doi: 10.4103/1673-5374.264447.

  9. Cell-Based Therapy for Stroke: Musing With Muse Cells.
    Park YJ, Niizuma K, Mokin M, Dezawa M, Borlongan CV.
    Stroke. 2020;51(9):2854-2862. doi: 10.1161/STROKEAHA.120.030618.

  10. What does computational fluid dynamics tell us about intracranial aneurysms? A meta-analysis and critical review.
    Saqr KM, Rashad S, Tupin S, Niizuma K, Hassan T, Tominaga T, Ohta M.
    J Cereb Blood Flow Metab. 2020;40(5):1021-1039. doi: 10.1177/0271678X19854640.

  11. [Actualization of Neural Regenerative Medicine by Intravenous Drip of Donor-derived Muse Cells].
    Dezawa M, Niizuma K, Tominaga T.
    Brain Nerve. 2019;71(8):895-900. doi: 10.11477/mf.1416201372. Article in Japanese.

  12. Accelerating Cell Therapy for Stroke in Japan: Regulatory Framework and Guidelines on Development of Cell-Based Products.
    Houkin K, Shichinohe H, Abe K, Arato T, Dezawa M, Honmou O, Horie N, Katayama Y, Kudo K, Kuroda S, Matsuyama T, Miyai I, Nagata I, Niizuma K, Sakushima K, Sasaki M, Sato N, Sawanobori K, Suda S, Taguchi A, Tominaga T, Yamamoto H, et al.
    Stroke. 2018;49(4):e145-e152. doi: 10.1161/STROKEAHA.117.019216.

  13. [Current Indications and Problems of CEA and CAS].
    Endo H, Fujimura M, Matsumoto Y, Endo T, Sato K, Niizuma K, Inoue T, Tominaga T.
    Jpn J Neurosurgery. 2018;27(7):514-521. doi: 10.7887/jcns.27.514. Article in Japanese.